LDAH

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LDAH RNA expression is significantly associated with the protein abundance of many other proteins, with 11,256 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LDAH-associated proteins across cancer lineages are RNF20, WDR5, and WRNIP1. Each is linked with LDAH in more than 4 cancer types. Because this analysis shows association rather than direction, both LDAH-to-partner and partner-to-LDAH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDAH versus RNF20 in LSCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LDAH→partner) and Y-score (partner→LDAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRNF20 →+0.219+0.518<.001<.00135
GBMWDR5 →+0.324+0.442<.001.00135
GBMWRNIP1 →+0.360+0.437<.001<.00134
LSCCRIF1 →+0.371+0.359<.001<.00134
GBMPOLDIP3 →+0.354+0.393<.001.00134
GBMRAB32 →-0.285-0.310.005.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,256 associations by consensus.

LDAH vs RNF20 — LSCC

Per-sample scatter of LDAH vs RNF20 in LSCC (Pearson r = 0.31).

Explore this scatter interactively →

Exploration