LDAH

Across TCGA patient cohorts, LDAH protein abundance is significantly associated with the RNA expression of many other genes, with 6,307 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LDAH-associated genes across cancer lineages are LRRC4, BABAM1, and CDKN2C. Each is linked with LDAH in more than 2 cancer types. Because this analysis shows association rather than direction, both LDAH-to-partner and partner-to-LDAH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LDAH versus LRRC4 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDAH→partner) and Y-score (partner→LDAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LRRC4 →	+0.962	+0.220	<.001	.006	3	3
GBM	BABAM1 →	-0.275	-0.396	<.001	<.001	3	3
GBM	CDKN2C →	-0.947	-0.332	.001	.001	3	3
UCEC	MRAP2 →	-1.085	-0.496	<.001	<.001	3	3
CCRCC	LAMB3 →	-0.934	-0.207	.002	.002	3	3
HNSC	HIPK2 →	+0.606	+0.290	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,307 associations by consensus.

LDAH vs LRRC4 — HNSC

Explore this scatter interactively →