LCP2

Across TCGA cell cohorts, LCP2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LCP2-associated genes across cancer lineages are FAM90A26, OR1A2, and PF4V1. Each is linked with LCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCP2-to-partner and partner-to-LCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM90A26 grouped by LCP2-low versus LCP2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCP2→partner) and Y-score (partner→LCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	FAM90A26 →	+0.012	+4.285	<.001	.007	3	2
OVARY	OR1A2 →	+0.036	+5.807	<.001	.001	3	1
STOMACH	PF4V1 →	+0.683	+4.432	<.001	.003	3	1
STOMACH	OR2V2 →	+0.013	+4.432	.003	.003	3	1
STOMACH	GPR33 →	+0.027	+4.129	<.001	.007	3	1
STOMACH	KDM4E →	+0.016	+4.432	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

FAM90A26 by LCP2 expression — STOMACH

Explore this box plot interactively →