LCP1

Across TCGA pan-cancer cohorts, LCP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated LCP1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LCP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LCP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

COAD, PDAC, and HNSC are the cancer types where LCP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.875	1.000	.015	84	view →
PDAC	OS	Tertile	All	0.809	0.408	<.001	51	view →
HNSC	DFS	Median	II,III,IV	0.678	0.890	.003	22	view →
GBM	DFS	Quartile	All	0.228	0.442	.002	10	view →
LUAD	DFS	Quartile	All	0.785	0.392	.021	9	view →
LSCC	DFS	Median	II,III,IV	0.560	0.824	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

LCP1–COAD (DFS)

Open the COAD breakdown →