Across TCGA patient cohorts, LCOR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LCOR-associated proteins across cancer lineages are NHLRC2, GATAD2B, and PYGL. Each is linked with LCOR in more than 4 cancer types. Because this analysis shows association rather than direction, both LCOR-to-partner and partner-to-LCOR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LCOR→partner) and Y-score (partner→LCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NHLRC2 →	+0.228	+0.326	<.001	<.001	3	5
LSCC	GATAD2B →	+0.324	+0.578	<.001	<.001	3	5
HNSC	PYGL →	-0.475	-0.305	.001	.005	3	4
GBM	VPS72 →	+0.374	+0.290	.004	.004	3	4
HNSC	WAPL →	+0.164	+0.360	.001	.002	3	4
HNSC	WDR5 →	+0.244	+0.503	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,266 associations by consensus.

Exploration

LCOR survival (RNA) · tumor vs normal (RNA) · all LCOR data types