Across TCGA cell cohorts, LCOR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,169 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LCOR-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Regulation of sister chromatid cohesion, and Protein modification by small protein removal. Each is linked with LCOR in more than 14 cancer types. Because this analysis shows association rather than direction, both LCOR-to-partner and partner-to-LCOR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCOR→partner) and Y-score (partner→LCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of gene expression, epigenetic →	+0.070	+0.793	.006	<.001	3	15
OVARY	Regulation of sister chromatid cohesion →	+0.128	+0.719	<.001	<.001	3	15
SOFT_TISSUE	Protein modification by small protein removal →	+0.054	+0.662	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.111	+0.671	<.001	.001	3	15
BONE	Heterochromatin formation →	+0.083	+0.870	.007	.001	3	15
BONE	Heterochromatin organization →	+0.079	+0.735	.008	.007	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,169 associations by consensus.

Exploration

LCOR survival (RNA) · tumor vs normal (RNA) · all LCOR data types