Across TCGA cell cohorts, LCOR mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCOR-associated genes across cancer lineages are C6orf118, BPIFB6, and PRAMEF20. Each is linked with LCOR in more than 1 cancer types. Because this analysis shows association rather than direction, both LCOR-to-partner and partner-to-LCOR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCOR→partner) and Y-score (partner→LCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.122	+3.115	<.001	.004	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR5V1 →	+0.005	+3.700	<.001	.009	3	1
LARGE_INTESTINE	INSRR →	+0.028	+3.584	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

LCOR survival (RNA) · tumor vs normal (RNA) · all LCOR data types