LCN9

Across TCGA patient cohorts, LCN9 mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible LCN9-associated genes across cancer lineages are MIR574, TBC1D3P4, and RNU6-784P. Each is linked with LCN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCN9-to-partner and partner-to-LCN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR574 grouped by LCN9-low versus LCN9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN9→partner) and Y-score (partner→LCN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR574 →	+0.510	+2.885	.003	.006	3	2
BLCA	TBC1D3P4 →	+0.033	+5.444	<.001	.002	3	2
BLCA	RNU6-784P →	+0.584	+5.435	<.001	<.001	3	2
BLCA	MIR1224 →	+0.465	+5.444	<.001	.002	3	2
COAD	ATP5PBP4 →	+0.073	+6.409	<.001	<.001	3	1
COAD	RPL7P29 →	+0.202	+4.478	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

MIR574 by LCN9 expression — UCEC

Explore this box plot interactively →