LCN6

Across TCGA pan-cancer cohorts, LCN6 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LCN6 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LCN6 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LCN6 expression acts as an unfavorable survival marker.

COAD, STAD, and BRCA are the cancer types where LCN6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.165	0.689	.020	24	view →
STAD	OS	Median	III,IV	0.003	0.633	<.001	12	view →
BRCA	OS	Median	All	0.175	0.579	.028	8	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LCN6–COAD (DFS)

Open the COAD breakdown →