LCN2

Across TCGA patient cohorts, LCN2 RNA expression is significantly associated with the RNA expression of many other genes, with 12,167 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible LCN2-associated genes across cancer lineages are CXCL1, SLPI, and PDZK1IP1. Each is linked with LCN2 in more than 29 cancer types. Because this analysis shows association rather than direction, both LCN2-to-partner and partner-to-LCN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCN2 versus CXCL1 in UCS, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN2→partner) and Y-score (partner→LCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	CXCL1 →	+2.269	+2.591	<.001	<.001	3	30
UCS	SLPI →	+3.804	+3.283	<.001	<.001	3	29
BLCA	PDZK1IP1 →	+2.978	+3.361	<.001	<.001	3	28
BLCA	PI3 →	+3.071	+2.426	<.001	<.001	3	27
UCS	LRG1 →	+2.641	+4.365	<.001	<.001	3	26
BLCA	TCN1 →	+1.963	+1.810	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,167 associations by consensus.

LCN2 vs CXCL1 — UCS

Explore this scatter interactively →