LCN2

Across TCGA patient cohorts, LCN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,855 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LCN2-associated proteins across cancer lineages are S100P, GOLGA1, and PIGR_S673. Each is linked with LCN2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LCN2-to-partner and partner-to-LCN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCN2 versus S100P in UCEC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN2→partner) and Y-score (partner→LCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S100P →	+1.427	+2.654	<.001	<.001	3	7
OV	GOLGA1 →	+0.259	+1.661	.002	.002	3	6
BRCA	PIGR_S673 →	+1.956	+2.364	<.001	<.001	3	5
GBM	S100A9 →	+1.437	+0.796	<.001	<.001	3	5
LSCC	NIBAN2 →	+0.506	+2.561	<.001	<.001	3	5
OV	ARL3 →	-0.453	-3.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,855 associations by consensus.

LCN2 vs S100P — UCEC

Explore this scatter interactively →