LCN2

Across TCGA patient cohorts, LCN2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCN2-associated genes across cancer lineages are Basophils, CMP, and MEP. Each is linked with LCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCN2-to-partner and partner-to-LCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by LCN2-low versus LCN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN2→partner) and Y-score (partner→LCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Basophils →	+0.181	+2.832	.016	.034	3	2
LUSC	CMP →	+0.019	+3.315	.041	.040	3	1
UCEC	MEP →	+0.031	+2.839	.030	.035	3	1
UCEC	Th1 cells →	+0.118	+3.321	.016	.010	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Basophils by LCN2 expression — SKCM

Explore this box plot interactively →