LCN15

Across TCGA cell cohorts, LCN15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,226 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LCN15-associated GO terms across cancer lineages are Ubiquinone metabolic process, Protein activation cascade, and Quinone biosynthetic process. Each is linked with LCN15 in more than 5 cancer types. Because this analysis shows association rather than direction, both LCN15-to-partner and partner-to-LCN15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquinone metabolic process grouped by LCN15-low versus LCN15-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN15→partner) and Y-score (partner→LCN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Ubiquinone metabolic process →	+0.076	+0.042	<.001	.003	3	6
SOFT_TISSUE	Protein activation cascade →	-0.274	-0.086	<.001	.004	3	6
PANCREAS	Quinone biosynthetic process →	+0.076	+0.044	<.001	.001	3	5
BONE	Positive regulation of monoatomic ion transport →	-0.143	-0.309	<.001	<.001	3	5
PANCREAS	Ubiquinone biosynthetic process →	+0.076	+0.044	<.001	.001	3	5
SOFT_TISSUE	Blood coagulation, fibrin clot formation →	-0.278	-0.157	<.001	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,226 associations by consensus.

Ubiquinone metabolic process by LCN15 expression — PANCREAS

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