Across TCGA patient cohorts, LCN10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,139 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCN10-associated GO terms across cancer lineages are Negative regulation of kinase activity, Nuclear export, and Glycerophospholipid metabolic process. Each is linked with LCN10 in more than 27 cancer types. Because this analysis shows association rather than direction, both LCN10-to-partner and partner-to-LCN10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN10→partner) and Y-score (partner→LCN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of kinase activity →	+0.053	+0.190	<.001	<.001	3	27
DLBC	Nuclear export →	+0.064	+0.225	.005	.002	1	28
STAD	Glycerophospholipid metabolic process →	+0.041	+0.172	<.001	<.001	3	26
ESCA	Insulin receptor signaling pathway →	+0.073	+0.196	<.001	<.001	3	26
STAD	Golgi to plasma membrane transport →	+0.072	+0.196	<.001	<.001	3	26
STAD	Vacuolar transport →	+0.055	+0.173	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,139 associations by consensus.

Exploration

LCN10 survival (RNA) · tumor vs normal (RNA) · all LCN10 data types