Across TCGA patient cohorts, LCN10 protein abundance is significantly associated with the RNA expression of many other genes, with 185 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LCN10-associated genes across cancer lineages are RIMS4, MAGED2, and KLF5. Each is linked with LCN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCN10-to-partner and partner-to-LCN10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN10→partner) and Y-score (partner→LCN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RIMS4 →	+2.553	+0.419	.002	.004	3	1
BRCA	MAGED2 →	+1.468	+0.504	.002	.004	3	1
BRCA	KLF5 →	-2.005	-0.493	.004	.008	3	1
BRCA	EARS2 →	+1.032	+0.513	<.001	.001	3	1
BRCA	NOMO1 →	+0.655	+0.392	.001	.008	3	1
BRCA	TRPS1 →	+2.218	+0.521	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 185 associations by consensus.

Exploration

LCN10 survival (RNA) · tumor vs normal (RNA) · all LCN10 data types