Across TCGA patient cohorts, LCN10 mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCN10-associated genes across cancer lineages are SLC20A1P1, PRAMEF28P, and RPS29P32. Each is linked with LCN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCN10-to-partner and partner-to-LCN10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN10→partner) and Y-score (partner→LCN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SLC20A1P1 →	+0.034	+5.969	.001	.002	3	2
UCEC	PRAMEF28P →	+0.066	+3.136	.001	.007	3	1
UCEC	RPS29P32 →	+0.417	+2.792	.003	.006	3	1
CESC	MIR920 →	+0.438	+5.539	<.001	.004	3	1
CESC	OR2W4P →	+0.054	+5.812	<.001	.003	3	1
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

Exploration

LCN10 survival (RNA) · tumor vs normal (RNA) · all LCN10 data types