LCMT2

Across TCGA patient cohorts, LCMT2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,612 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LCMT2-associated genes across cancer lineages are HMGB3P1, DGCR6, and AKR1B1P2. Each is linked with LCMT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCMT2-to-partner and partner-to-LCMT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCMT2 versus HMGB3P1 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCMT2→partner) and Y-score (partner→LCMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HMGB3P1 →	+0.638	+0.596	.007	.006	3	2
LSCC	DGCR6 →	-0.420	-0.716	.003	.001	3	2
BRCA	AKR1B1P2 →	-0.429	-0.332	.008	.001	3	2
BRCA	RPS4XP3 →	-1.547	-0.417	<.001	.001	3	2
BRCA	RHOQP3 →	-0.605	-0.376	.001	.005	3	2
BRCA	RPS18P12 →	-0.696	-0.401	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,612 associations by consensus.

LCMT2 vs HMGB3P1 — OV

Explore this scatter interactively →