LCMT1-AS2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LCMT1-AS2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LCMT1-AS2 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LCMT1-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LCMT1-AS2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

COAD, THCA, and CESC are the cancer types where LCMT1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianII,III,IV0.7930.901.00157view →
THCAOSQuartileII,III,IV0.6221.000.00246view →
CESCOSQuartileAll0.7050.851.00938view →
LIHCDFSQuartileAll0.2560.511.00121view →
ESCAOSMedianIII,IV0.6330.324.00520view →
BRCADFSTertileIII,IV0.8500.711.01219view →
BLCADFSTertileAll0.4300.686.00318view →
LUSCOSMedianIV0.0570.786.01718view →
LAMLDFSMedianAll0.6020.329.00818view →
READOSTertileII,III,IV1.0000.436.01116view →
KICHOSTertileIII,IV1.0000.437.01210view →
ACCDFSMedianIII,IV0.4250.112.0169view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LCMT1-AS2–COAD (OS)

Kaplan–Meier survival curve for LCMT1-AS2 RNA-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration