LCMT1-AS1

Across TCGA pan-cancer cohorts, LCMT1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LCMT1-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LCMT1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LCMT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and PAAD show a favorable association.

UVM, KIRC, and PAAD are the cancer types where LCMT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.910	0.563	<.001	110	view →
KIRC	OS	Median	All	0.558	0.726	<.001	92	view →
PAAD	DFS	Tertile	All	0.443	0.187	<.001	75	view →
COAD	OS	Quartile	II,III,IV	0.457	0.774	.002	59	view →
LUAD	OS	Median	All	0.850	0.771	.004	58	view →
ACC	DFS	Tertile	All	0.574	0.818	.006	36	view →
ESCA	OS	Median	IV	0.698	0.222	.006	21	view →
HNSC	DFS	Quartile	All	0.832	0.526	<.001	20	view →
LUSC	DFS	Tertile	III,IV	0.409	0.951	.004	18	view →
KIRP	OS	Tertile	III,IV	0.262	0.841	.001	12	view →
LGG	OS	Median	All	0.939	0.842	.002	12	view →
BLCA	DFS	Tertile	All	0.297	0.476	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LCMT1-AS1–UVM (DFS)

Open the UVM breakdown →