LCLAT1

Across TCGA patient cohorts, LCLAT1 mutation is significantly associated with the RNA expression of many other genes, with 2,089 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCLAT1-associated genes across cancer lineages are TSPY12P, KHDC1P1, and MIR4774. Each is linked with LCLAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LCLAT1-to-partner and partner-to-LCLAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY12P grouped by LCLAT1-low versus LCLAT1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCLAT1→partner) and Y-score (partner→LCLAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TSPY12P →	+0.018	+4.590	<.001	.004	3	3
READ	KHDC1P1 →	+0.108	+6.257	<.001	.001	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
LUAD	PAX4 →	+0.269	+4.005	<.001	<.001	3	2
LUAD	ZNF92P1Y →	+0.015	+6.020	<.001	<.001	3	2
LUAD	RPS15P9 →	+0.451	+4.100	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,089 associations by consensus.

TSPY12P by LCLAT1 expression — LUAD

Explore this box plot interactively →