LCLAT1

Across TCGA cell cohorts, LCLAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,569 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCLAT1-associated GO terms across cancer lineages are Phosphatidylinositol acyl-chain remodeling, Cardiolipin metabolic process, and Positive regulation of cell cycle. Each is linked with LCLAT1 in more than 19 cancer types. Because this analysis shows association rather than direction, both LCLAT1-to-partner and partner-to-LCLAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol acyl-chain remodeling grouped by LCLAT1-low versus LCLAT1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCLAT1→partner) and Y-score (partner→LCLAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Phosphatidylinositol acyl-chain remodeling →	+0.205	+1.115	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Cardiolipin metabolic process →	+0.119	+1.185	<.001	<.001	3	14
OESOPHAGUS	Positive regulation of cell cycle →	+0.087	+0.850	.003	.003	3	12
OESOPHAGUS	Regulation of double-strand break repair via homologous recombination →	+0.098	+1.031	.001	.001	3	11
LUNG_NSCLC_LUSC	Epigenetic regulation of gene expression →	+0.077	+1.178	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of cell division →	+0.076	+0.577	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,569 associations by consensus.

Phosphatidylinositol acyl-chain remodeling by LCLAT1 expression — STOMACH

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