Across TCGA patient cohorts, LCK RNA expression is significantly associated with the protein abundance of many other proteins, with 18,005 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LCK-associated proteins across cancer lineages are CORO1A, DEF6, and DOCK2. Each is linked with LCK in more than 9 cancer types. Because this analysis shows association rather than direction, both LCK-to-partner and partner-to-LCK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LCK→partner) and Y-score (partner→LCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CORO1A →	+0.695	+1.048	<.001	<.001	3	10
GBM	DEF6 →	+0.591	+0.918	<.001	<.001	3	10
OV	DOCK2 →	+0.685	+1.269	<.001	<.001	3	10
GBM	DOCK8 →	+0.550	+0.967	<.001	<.001	3	10
GBM	LCP1 →	+0.852	+0.994	<.001	<.001	3	10
GBM	ARHGAP15 →	+0.774	+0.988	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,005 associations by consensus.

Exploration

LCK survival (RNA) · tumor vs normal (RNA) · all LCK data types