Across TCGA cell cohorts, LCK RNA expression is significantly associated with the RNA expression of many other genes, with 10,316 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LCK-associated genes across cancer lineages are IL23A, ST14, and CD79A. Each is linked with LCK in more than 7 cancer types. Because this analysis shows association rather than direction, both LCK-to-partner and partner-to-LCK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCK→partner) and Y-score (partner→LCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IL23A →	+2.296	+1.197	<.001	.001	3	8
LUNG_NSCLC_LUSC	ST14 →	+4.429	+0.828	<.001	.008	2	8
BLOOD_Leukemia	CD79A →	+4.663	+3.739	<.001	<.001	3	6
BLOOD_Lymphoma	HDAC1 →	+1.273	+3.954	<.001	<.001	3	6
LUNG_SCLC	EPCAM →	+3.552	+2.052	<.001	<.001	3	6
URINARY_TRACT	SH2D3A →	+2.827	+0.783	.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,316 associations by consensus.

Exploration

LCK survival (RNA) · tumor vs normal (RNA) · all LCK data types