Across TCGA patient cohorts, LCE4A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,900 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCE4A-associated GO terms across cancer lineages are Pyrimidine ribonucleoside monophosphate biosynthetic process, Neuroepithelial cell differentiation, and Icosanoid metabolic process. Each is linked with LCE4A in more than 3 cancer types. Because this analysis shows association rather than direction, both LCE4A-to-partner and partner-to-LCE4A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE4A→partner) and Y-score (partner→LCE4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pyrimidine ribonucleoside monophosphate biosynthetic process →	+0.086	+0.072	<.001	.008	3	3
STAD	Neuroepithelial cell differentiation →	+0.076	+0.080	<.001	.003	3	3
STAD	Icosanoid metabolic process →	+0.074	+0.039	<.001	.006	3	3
STAD	Endosomal lumen acidification →	+0.103	+0.041	<.001	.004	2	4
STAD	Telencephalon development →	+0.082	+0.066	<.001	.004	3	3
STAD	Anatomical structure maturation →	+0.064	+0.069	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,900 associations by consensus.

Exploration

LCE4A survival (RNA) · tumor vs normal (RNA) · all LCE4A data types