Across TCGA cell cohorts, LCE3B RNA expression is significantly associated with the mutation status of many other genes, with 8 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible LCE3B-associated genes across cancer lineages are RIN2, RSPO3, and ST14. Each is linked with LCE3B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3B-to-partner and partner-to-LCE3B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3B→partner) and Y-score (partner→LCE3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RIN2 →	+4.357	+0.100	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	RSPO3 →	+5.357	+0.133	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ST14 →	+4.357	+0.100	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF618 →	+4.357	+0.100	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	CEP290 →	+5.357	+0.133	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	NBPF14 →	+4.357	+0.100	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

LCE3B survival (RNA) · tumor vs normal (RNA) · all LCE3B data types