Across TCGA patient cohorts, LCE3A protein abundance is significantly associated with the RNA expression of many other genes, with 1,003 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE3A-associated genes across cancer lineages are MFNG, DNAL4, and APOBEC3H. Each is linked with LCE3A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3A-to-partner and partner-to-LCE3A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3A→partner) and Y-score (partner→LCE3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MFNG →	-0.700	-1.185	.002	.003	3	1
HNSC	DNAL4 →	-0.618	-1.099	.002	.007	3	1
HNSC	APOBEC3H →	-0.702	-1.509	<.001	<.001	3	1
HNSC	DCAF11 →	-0.663	-1.080	.002	.008	3	1
HNSC	PFDN4 →	-0.536	-1.412	.003	.006	3	1
HNSC	CTSZ →	-0.955	-1.275	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,003 associations by consensus.

Exploration

LCE3A survival (RNA) · tumor vs normal (RNA) · all LCE3A data types