LCE1F

Across TCGA pan-cancer cohorts, LCE1F Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LCE1F data layer compared with 14 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher LCE1F Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LCE1F expression acts as an unfavorable survival marker.

READ, LUAD, and LIHC are the cancer types where LCE1F Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.054	0.934	<.001	24	view →
LUAD	OS	Median	II,III,IV	0.090	0.677	<.001	18	view →
LIHC	OS	Median	All	0.083	0.783	<.001	12	view →
LUSC	OS	Median	II,III,IV	0.181	0.742	.007	12	view →
COAD	OS	Median	All	0.210	0.799	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LCE1F–READ (OS)

Open the READ breakdown →