Across TCGA pan-cancer cohorts, LCE1E Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LCE1E data layer compared with 15 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LCE1E Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LCE1E expression acts as an unfavorable survival marker.

COAD and STAD are the cancer types where LCE1E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.249	0.809	<.001	15	view →
STAD	OS	Median	IV	0.075	0.496	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LCE1E tumor-vs-normal RNA expression · all LCE1E data types