Across TCGA patient cohorts, LCE1C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,760 significant associations in total. THCA shows the largest number of these associations.

The most reproducible LCE1C-associated GO terms across cancer lineages are Hemidesmosome assembly, Intermediate filament organization, and Regulation of epidermis development. Each is linked with LCE1C in more than 8 cancer types. Because this analysis shows association rather than direction, both LCE1C-to-partner and partner-to-LCE1C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1C→partner) and Y-score (partner→LCE1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Hemidesmosome assembly →	+0.122	+0.681	<.001	<.001	3	9
ESCA	Intermediate filament organization →	+0.096	+0.757	<.001	<.001	3	8
ESCA	Regulation of epidermis development →	+0.057	+0.713	<.001	<.001	3	8
ESCA	Skin epidermis development →	+0.053	+0.744	<.001	<.001	3	8
ESCA	Epidermal cell differentiation →	+0.066	+0.628	<.001	<.001	3	8
ESCA	Positive regulation of keratinocyte proliferation →	+0.129	+0.551	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,760 associations by consensus.

Exploration

LCE1C survival (RNA) · tumor vs normal (RNA) · all LCE1C data types