Across TCGA cell cohorts, LCE1C mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCE1C-associated genes across cancer lineages are GHRHR, MYH1, and ZAN. Each is linked with LCE1C in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1C-to-partner and partner-to-LCE1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1C→partner) and Y-score (partner→LCE1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GHRHR →	+0.084	+4.054	<.001	.004	3	1
LARGE_INTESTINE	MYH1 →	+0.096	+3.684	.005	.006	3	1
LARGE_INTESTINE	ZAN →	+0.010	+4.882	.001	<.001	3	1
LARGE_INTESTINE	SLC22A8 →	+0.028	+4.196	<.001	.002	3	1
LARGE_INTESTINE	ADH1A →	+0.147	+3.920	<.001	.005	3	1
LARGE_INTESTINE	MYH13 →	+0.703	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

LCE1C survival (RNA) · tumor vs normal (RNA) · all LCE1C data types