Across TCGA patient cohorts, LCE1B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE1B-associated genes across cancer lineages are C-Raf, Caspase-8, and G6PD. Each is linked with LCE1B in more than 2 cancer types. Because this analysis shows association rather than direction, both LCE1B-to-partner and partner-to-LCE1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1B→partner) and Y-score (partner→LCE1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	C-Raf →	+0.171	+2.321	.003	.033	3	3
UCEC	Caspase-8 →	-0.263	-3.295	.030	.009	3	2
SKCM	G6PD →	-0.228	-3.584	.009	.002	3	1
SKCM	Bcl-xL →	-0.180	-2.446	.016	.018	3	1
SKCM	Chk1 →	+0.318	+1.749	<.001	.049	3	1
UCEC	FoxM1 →	+0.316	+3.584	.011	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

LCE1B survival (RNA) · tumor vs normal (RNA) · all LCE1B data types