Across TCGA cell cohorts, LCE1B mutation is significantly associated with the mutation status of many other genes, with 408 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LCE1B-associated genes across cancer lineages are ZNF585A, LRIG2, and CCDC174. Each is linked with LCE1B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1B-to-partner and partner-to-LCE1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1B→partner) and Y-score (partner→LCE1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF585A →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	LRIG2 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	CCDC174 →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	ACSS1 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	ZFYVE28 →	+4.000	+5.050	.008	.008	1	2
LARGE_INTESTINE	ZNF597 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

Exploration

LCE1B survival (RNA) · tumor vs normal (RNA) · all LCE1B data types