Across TCGA cell cohorts, LCAT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,645 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LCAT-associated GO terms across cancer lineages are Endosomal transport, mRNA splice site recognition, and Vacuole organization. Each is linked with LCAT in more than 13 cancer types. Because this analysis shows association rather than direction, both LCAT-to-partner and partner-to-LCAT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCAT→partner) and Y-score (partner→LCAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endosomal transport →	+0.065	+1.471	.005	.003	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.133	+1.170	<.001	<.001	3	13
BONE	Vacuole organization →	+0.065	+1.903	<.001	<.001	3	13
SKIN	Ascending thin limb development →	+0.294	+1.058	<.001	<.001	3	13
SKIN	Metanephric ascending thin limb development →	+0.294	+1.058	<.001	<.001	3	13
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.135	+1.884	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,645 associations by consensus.

Exploration

LCAT survival (RNA) · tumor vs normal (RNA) · all LCAT data types