LCA5

Across TCGA patient cohorts, LCA5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,057 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCA5-associated genes across cancer lineages are C6orf118, CFAP94, and CFAP58. Each is linked with LCA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both LCA5-to-partner and partner-to-LCA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCA5 versus C6orf118 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCA5→partner) and Y-score (partner→LCA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C6orf118 →	+1.744	+0.577	<.001	<.001	3	3
UCEC	CFAP94 →	+0.916	+0.437	<.001	.004	3	3
UCEC	CFAP58 →	+0.795	+0.569	<.001	<.001	3	3
UCEC	DNAI1 →	+1.972	+0.541	<.001	.001	3	3
UCEC	CDHR3 →	+1.909	+0.779	<.001	<.001	3	3
UCEC	RGS22 →	+1.448	+0.721	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,057 associations by consensus.

LCA5 vs C6orf118 — UCEC

Explore this scatter interactively →