LBX2

Across TCGA patient cohorts, LBX2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LBX2-associated genes across cancer lineages are CD8+ T-cells, CD4+ naive T-cells, and CD8+ Tcm. Each is linked with LBX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LBX2-to-partner and partner-to-LBX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by LBX2-low versus LBX2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBX2→partner) and Y-score (partner→LBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD8+ T-cells →	+0.059	+5.142	<.001	.041	3	2
COAD	CD4+ naive T-cells →	+0.031	+5.142	<.001	.041	3	2
COAD	CD8+ Tcm →	+0.101	+4.917	<.001	.048	3	1
UCEC	CD8+ Tem →	+0.005	+5.258	<.001	.029	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ T-cells by LBX2 expression — COAD

Explore this box plot interactively →