LBX2

Across TCGA cell cohorts, LBX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,959 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LBX2-associated GO terms across cancer lineages are Regulation of telomere maintenance, Cardiac muscle cell action potential involved in contraction, and Tongue morphogenesis. Each is linked with LBX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LBX2-to-partner and partner-to-LBX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by LBX2-low versus LBX2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LBX2→partner) and Y-score (partner→LBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of telomere maintenance →	+0.048	+1.083	.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Cardiac muscle cell action potential involved in contraction →	-0.139	-0.759	<.001	<.001	3	8
KIDNEY	Tongue morphogenesis →	-0.236	-1.499	<.001	<.001	3	8
KIDNEY	Vacuolar transport →	+0.062	+1.273	<.001	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.104	+0.883	.001	.001	3	7
BLOOD_Lymphoma	Negative regulation of post-translational protein modification →	+0.088	+1.222	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,959 associations by consensus.

Regulation of telomere maintenance by LBX2 expression — SOFT_TISSUE

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