LBP

Across TCGA pan-cancer cohorts, LBP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LBP data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LBP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated LBP expression acts as an unfavorable survival marker.

CCRCC, COAD, and LUAD are the cancer types where LBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.513	0.839	.001	64	view →
COAD	DFS	Tertile	All	0.869	1.000	.037	24	view →
LUAD	OS	Quartile	III,IV	0.304	0.840	.006	15	view →
LSCC	DFS	Median	II,III,IV	0.830	1.000	.003	12	view →
GBM	DFS	Median	All	0.284	0.469	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LBP–CCRCC (OS)

Open the CCRCC breakdown →