LBHD2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LBHD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 747 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LBHD2-associated GO terms across cancer lineages are Proton transmembrane transport, Cellular respiration, and Anterior/posterior axis specification. Each is linked with LBHD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LBHD2-to-partner and partner-to-LBHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by LBHD2-low versus LBHD2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LBHD2→partner) and Y-score (partner→LBHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADProton transmembrane transport →+0.042+0.179.004.00735
OVARYCellular respiration →+0.083+0.406<.001.00235
LUNG_NSCLC_LUADAnterior/posterior axis specification →-0.051-0.166.001<.00134
BONERibonucleotide biosynthetic process →+0.066+0.621.005.00634
OVARYEnergy derivation by oxidation of organic compounds →+0.062+0.416<.001<.00134
PANCREASMaintenance of protein localization in organelle →+0.083+0.353.001.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

Proton transmembrane transport by LBHD2 expression — LUNG_NSCLC_LUAD

Box plot of Proton transmembrane transport in LBHD2-low vs LBHD2-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration