LBHD1

Across TCGA cell cohorts, LBHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,428 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LBHD1-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, and Regulation of RNA splicing. Each is linked with LBHD1 in more than 10 cancer types. Because this analysis shows association rather than direction, both LBHD1-to-partner and partner-to-LBHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by LBHD1-low versus LBHD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LBHD1→partner) and Y-score (partner→LBHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.111	+1.342	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.121	+1.171	<.001	<.001	3	10
KIDNEY	Regulation of RNA splicing →	+0.061	+0.837	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.094	+1.046	.001	.003	3	8
STOMACH	Mitochondrial electron transport, succinate to ubiquinone →	+0.065	+0.807	.004	.003	3	8
KIDNEY	RNA catabolic process →	+0.059	+1.083	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,428 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by LBHD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →