Across TCGA patient cohorts, LBH RNA expression is significantly associated with the protein abundance of many other proteins, with 15,160 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LBH-associated proteins across cancer lineages are CALD1, FBLIM1, and FILIP1L. Each is linked with LBH in more than 7 cancer types. Because this analysis shows association rather than direction, both LBH-to-partner and partner-to-LBH results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LBH→partner) and Y-score (partner→LBH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CALD1 →	+0.622	+0.797	<.001	<.001	3	8
GBM	FBLIM1 →	+0.733	+0.883	<.001	<.001	3	8
GBM	FILIP1L →	+0.549	+0.871	<.001	<.001	3	8
UCEC	TGFB1I1 →	+0.602	+0.748	<.001	<.001	3	8
COAD	TPM2 →	+0.668	+0.520	<.001	<.001	3	8
CCRCC	PDLIM7 →	+0.897	+0.711	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,160 associations by consensus.

Exploration

LBH survival (RNA) · tumor vs normal (RNA) · all LBH data types