Across TCGA patient cohorts, LBH mutation is significantly associated with the RNA expression of many other genes, with 3,539 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LBH-associated genes across cancer lineages are BNIP3P20, MIR6760, and RNU6-419P. Each is linked with LBH in more than 1 cancer types. Because this analysis shows association rather than direction, both LBH-to-partner and partner-to-LBH results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBH→partner) and Y-score (partner→LBH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	BNIP3P20 →	+0.107	+5.758	<.001	.003	3	1
LIHC	MIR6760 →	+0.702	+5.268	<.001	.006	3	1
LIHC	RNU6-419P →	+1.037	+5.268	<.001	.006	3	1
LIHC	LINC02420 →	+0.095	+5.544	<.001	.004	3	1
LIHC	GLRXP2 →	+0.185	+5.447	<.001	.005	3	1
LIHC	UBE2CP4 →	+0.157	+5.033	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,539 associations by consensus.

Exploration

LBH survival (RNA) · tumor vs normal (RNA) · all LBH data types