Across TCGA patient cohorts, LAYN RNA expression is significantly associated with the protein abundance of many other proteins, with 21,078 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LAYN-associated proteins across cancer lineages are SSC5D, CAVIN1, and CAVIN3. Each is linked with LAYN in more than 7 cancer types. Because this analysis shows association rather than direction, both LAYN-to-partner and partner-to-LAYN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAYN→partner) and Y-score (partner→LAYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SSC5D →	+0.786	+0.693	<.001	<.001	3	8
UCEC	CAVIN1 →	+0.915	+0.708	<.001	<.001	3	8
UCEC	CAVIN3 →	+0.798	+0.698	<.001	<.001	3	8
UCEC	ILK →	+0.574	+0.733	<.001	<.001	3	8
UCEC	KANK2 →	+0.732	+0.826	<.001	<.001	3	8
GBM	MYO1C →	+0.570	+0.985	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,078 associations by consensus.

Exploration

LAYN survival (RNA) · tumor vs normal (RNA) · all LAYN data types