Across TCGA cell cohorts, LAYN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,506 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LAYN-associated GO terms across cancer lineages are Negative regulation of cytokine production, Regulation of intracellular transport, and Regulation of intracellular protein transport. Each is linked with LAYN in more than 12 cancer types. Because this analysis shows association rather than direction, both LAYN-to-partner and partner-to-LAYN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAYN→partner) and Y-score (partner→LAYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cytokine production →	+0.066	+3.565	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of intracellular transport →	+0.060	+2.258	<.001	<.001	3	12
BREAST	Regulation of intracellular protein transport →	+0.075	+1.600	<.001	.003	3	12
BREAST	Negative regulation of molecular function →	+0.086	+1.848	<.001	<.001	2	13
BONE	Biological process involved in symbiotic interaction →	+0.141	+4.069	<.001	<.001	3	11
BONE	Cellular response to environmental stimulus →	+0.050	+3.485	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,506 associations by consensus.

Exploration

LAYN survival (RNA) · tumor vs normal (RNA) · all LAYN data types