LAT2

Across TCGA patient cohorts, LAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,530 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAT2-associated genes across cancer lineages are SRGN, LCP2, and CSF2RB. Each is linked with LAT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAT2-to-partner and partner-to-LAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAT2 versus SRGN in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT2→partner) and Y-score (partner→LAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRGN →	+1.157	+0.581	.001	.002	3	6
LSCC	LCP2 →	+0.719	+0.398	<.001	<.001	3	6
GBM	CSF2RB →	+1.366	+0.654	<.001	<.001	3	5
GBM	LILRB1 →	+1.108	+0.583	<.001	<.001	3	5
BRCA	JAK3 →	+1.030	+0.536	.004	.004	3	5
BRCA	LILRB2 →	+1.039	+0.636	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,530 associations by consensus.

LAT2 vs SRGN — BRCA

Explore this scatter interactively →