LAT2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LAT2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible LAT2-associated genes across cancer lineages are Monocytes. Each is linked with LAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LAT2-to-partner and partner-to-LAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by LAT2-low versus LAT2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT2→partner) and Y-score (partner→LAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCMonocytes →+0.014+5.305.007.04831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Monocytes by LAT2 expression — LIHC

Box plot of Monocytes in LAT2-low vs LAT2-high samples in LIHC.

Explore this box plot interactively →

Exploration