LAT2

Across TCGA cell cohorts, LAT2 RNA expression is significantly associated with the RNA expression of many other genes, with 8,482 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LAT2-associated genes across cancer lineages are ZMIZ2, SMURF2, and LIF. Each is linked with LAT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LAT2-to-partner and partner-to-LAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAT2 versus ZMIZ2 in OESOPHAGUS, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT2→partner) and Y-score (partner→LAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ZMIZ2 →	+1.124	+1.457	<.001	<.001	3	7
LARGE_INTESTINE	SMURF2 →	+1.277	+1.416	<.001	<.001	3	6
SKIN	LIF →	+2.397	+0.898	<.001	<.001	3	6
BLOOD_Leukemia	PTPRE →	+1.588	+3.533	<.001	<.001	3	6
LUNG_SCLC	ISG20 →	+1.661	+2.066	<.001	<.001	3	6
OESOPHAGUS	MAFF →	+1.318	+1.425	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,482 associations by consensus.

LAT2 vs ZMIZ2 — OESOPHAGUS

Explore this scatter interactively →