Across TCGA patient cohorts, LAT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible LAT-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of DNA metabolic process, and Positive regulation of double-strand break repair. Each is linked with LAT in more than 31 cancer types. Because this analysis shows association rather than direction, both LAT-to-partner and partner-to-LAT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT→partner) and Y-score (partner→LAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.055	+0.214	<.001	<.001	3	32
STAD	Positive regulation of DNA metabolic process →	+0.061	+0.262	<.001	<.001	3	31
STAD	Positive regulation of double-strand break repair →	+0.059	+0.241	<.001	<.001	3	31
KIRC	Positive regulation of DNA repair →	+0.055	+0.807	<.001	<.001	3	31
STAD	Protein K63-linked ubiquitination →	+0.068	+0.245	<.001	<.001	3	30
STAD	Protein localization to vacuole →	+0.070	+0.249	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Exploration

LAT survival (RNA) · tumor vs normal (RNA) · all LAT data types