Across TCGA patient cohorts, LAT mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LAT-associated genes across cancer lineages are CD8+ naive T-cells and Endothelial cells. Each is linked with LAT in more than 1 cancer types. Because this analysis shows association rather than direction, both LAT-to-partner and partner-to-LAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT→partner) and Y-score (partner→LAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.048	+2.839	.001	.034	3	1
UCEC	Endothelial cells →	-0.042	-3.127	.042	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

LAT survival (RNA) · tumor vs normal (RNA) · all LAT data types