LAT

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LAT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,194 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LAT-associated GO terms across cancer lineages are Late viral transcription, Regulation of myoblast fusion, and Regulation of RNA splicing. Each is linked with LAT in more than 9 cancer types. Because this analysis shows association rather than direction, both LAT-to-partner and partner-to-LAT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT→partner) and Y-score (partner→LAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUELate viral transcription →+0.129+0.921<.001.001310
UPPER_AERODIGESTIVE_TRACTRegulation of myoblast fusion →+0.099+1.135<.001<.00139
UPPER_AERODIGESTIVE_TRACTRegulation of RNA splicing →+0.068+0.802<.001<.00139
UPPER_AERODIGESTIVE_TRACTmRNA splice site recognition →+0.136+0.825<.001<.00139
UPPER_AERODIGESTIVE_TRACTNegative regulation of myoblast fusion →+0.105+1.104<.001<.00138
URINARY_TRACTDNA damage response, signal transduction by p53 class mediator →+0.086+1.844.005<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,194 associations by consensus.

Exploration