LARS2

Across TCGA patient cohorts, LARS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,525 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LARS2-associated proteins across cancer lineages are KIAA1143, TOP2B, and TRADD. Each is linked with LARS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LARS2-to-partner and partner-to-LARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LARS2 versus KIAA1143 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LARS2→partner) and Y-score (partner→LARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIAA1143 →	+0.379	+0.390	<.001	<.001	3	7
LSCC	TOP2B →	+0.424	+0.475	<.001	<.001	3	5
GBM	TRADD →	-0.343	-0.367	<.001	<.001	3	5
LSCC	FANCD2_S1435 →	+0.698	+0.395	<.001	<.001	3	5
GBM	FANCD2_S1412 →	+0.915	+0.395	.001	<.001	3	5
LSCC	U2SURP →	+0.345	+0.437	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,525 associations by consensus.

LARS2 vs KIAA1143 — BRCA

Explore this scatter interactively →